Publications:
1. Yang F*, Quan Z, Huang H, He M, Liu X, Cai T, and Xi R* (2019). Ovaries absent links dLsd1 to HP1a for local H3K4 demethylation required for heterochromatic gene silencing. Elife 2019 Jan 16;8. pii: e40806. doi: 10.7554/eLife.40806.
2. Zhang W, Zhang X, Xue Z, Li Y, Ma Q, Ren X, Zhang J, Yang S, Yang L, Wu M, Ren M, Xi R, Wu Z, Liu JL, Matunis E, Dai J, Gao G (2018). Probing the Function of Metazoan Histones with a Systematic Library of H3 and H4 Mutants. Dev 云顶集团(中国). pii: S1534-5807(18)31031-1. doi: 10.1016/j.devcel.2018.11.047.5807(18)31031-1
3. Chen J, Xu N, Wang C, Huang P, Huang H, Jin Z, Yu Z, Cai T, Jiao R, Xi R* (2018). Transient Scute activation via a self-stimulatory loop directs enteroendocrine 云顶集团(中国) pair specification from self-renewing intestinal stem 云顶集团(中国)s. Nat 云顶集团(中国) Biol. 20(2):152-161
4. Yin C, Xi R* (2018). A Phyllopod-Mediated Feedback Loop Promotes Intestinal Stem 云顶集团(中国) Enteroendocrine Commitment in Drosophila. Stem 云顶集团(中国) Reports. 9;10(1):43-57. doi: 10.1016/j.stemcr.2017.11.014.
5. Huang C, Yang F, Zhang Z, Zhang J, Cai G, Li L, Zheng Y, Chen S, Xi R*, Zhu B* (2017). Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila. Nat Commun. 8(1):1649. doi: 10.1038/s41467-017-01897-3.
6. Liu X, Wei W, Li X, Shen P, Ju D, Wang Z, Zhang R, Yang F, Chen C, Cao K, Zhu G, Chen H, Chen L, Sui J, Zhang E, Wu K, Wang F, Zhao L, Xi R* (2017). BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3. Gastroenterology. 2017 Aug 2. pii: S0016-5085(17)35976-0. doi: 10.1053/j.gastro.2017.07.044
7. Li Y*, Pang Z, Huang H, Wang C, Cai T, Xi R* (2017). Transcription Factor Antagonism Controls Enteroendocrine 云顶集团(中国) Specification from Intestinal Stem 云顶集团(中国)s. Sci Rep. 20;7(1):988. doi: 10.1038/s41598-017-01138-z.
8. Yang F, Xi R* (2017). Silencing transposable elements in the Drosophila germline. 云顶集团(中国) Mol Life Sci. 74(3):435-448 Review.
9. Chen J., Li J., Huang H. and Xi R*. (2016). Gene Expression Analysis of Sorted 云顶集团(中国)s by RNA-seq in Drosophila Intestine. Bio-protocol 6(24): e2079. DOI: 10.21769/BioProtoc.2079
10.Li X, Yang F, Chen H, Deng B, Li X, Xi R* (2016). Control of germline stem 云顶集团(中国) differentiation by polycomb and trithorax group genes in the niche microenvironment. Development. 143(19):3449-3458 pii: dev.137638.
11.Chen J, Xu N, Huang H, Cai T, Xi R* (2016). A feedback amplification loop between stem 云顶集团(中国)s and their progeny promotes tissue regeneration and tumorigenesis. Elife. 5. pii: e14330. doi: 10.7554/eLife.14330
12.Wang C, Xi R* (2015). Keeping intestinal stem 云顶集团(中国) differentiation on the Tramtrack. Fly (Austin). 14:0.
13.Hu Z, Hu Y, Liu X, Xi R, Zhang A, Liu D, Xie Q, Chen L (2015). Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor. Oncotarget. 6(31):31628-39
14.Wang C, Guo X, Dou K, Chen H, Xi R* (2015). Ttk69 acts as a master repressor of enteroendocrine 云顶集团(中国) specification in Drosophila intestinal stem 云顶集团(中国) lineages. Development 142(19):3321-31
15.Yang F, Zhao R, Fang X, Huang H, Xuan Y, Ma Y, Chen H, Cai T, Qi Y, Xi R* (2015). The RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in the Drosophila germline. EMBO Rep. 16(8):965-74
16.Guo X, Chen J, Li Z and Xi R* (2015). Signaling Pathways Regulating Stem 云顶集团(中国)s (Book Chapter) in R.C.Zhao (ed.), Stem 云顶集团(中国)s: Basics and Clinical Translation, Translational Medicine Research 1. Shanghai Jiaotong University Press, Shanghai and Springer Science+Business Media Dordrecht.
17.Wang C, Guo X, Xi R* (2014). EGFR and Notch signaling respectively regulate proliferative activity and multiple 云顶集团(中国) lineage differentiation of Drosophila gastric stem 云顶集团(中国)s. 云顶集团(中国) Research 24(5):610-27
18.Quan Z, Sun P, Lin G, Xi R* (2013). TSC1/2 regulates intestinal stem 云顶集团(中国) maintenance and lineage differentiation via Rheb-TORC1-S6K but independent of nutrition status or Notch regulation. J 云顶集团(中国) Sci. 126:3884-92
19.Wang C, Zhao R, Huang P, Yang F, Quan Z, Xu N, Xi R* (2013). APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression. Developmental Biology 378(2):122-40
20.Lin G, Zhang X, Ren J, Pang Z, Wang C, Xu N, Xi R* (2013). Integrin signaling is required for maintenance and proliferation of intestinal stem 云顶集团(中国)s in Drosophila. Developmental Biology377(1):177-87
21.Wen P, Quan Z, Xi R* (2012). The biological function of the WD40 repeat-containing protein p55/Caf1 in Drosophila. Developmental Dynamics 241(3):455-64
22.Xu N, Wang SQ, Tan D, Gao Y, Lin G, Xi R* (2011). EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem 云顶集团(中国)s. Developmental Biology 354(1):31-43
23.Su Y, Deng B, Xi R* (2011). Polycomb group genes in stem 云顶集团(中国) self-renewal: a double-edged sword. Epigenetics. 6(1):16-9.
24.Sun P, Quan Z, Zhang, B, Wu T, Xi R* (2010). TSC1/2 tumour suppressor complex maintains Drosophila germline stem 云顶集团(中国)s by preventing differentiation. Development 137(15):2461-9
25.Wen P, Sun P, Xi R* (2010). Stem 云顶集团(中国) niche (book chapter) in “Regenerative Medicine – From Protocol to Patient”. The Springer Press.
26.Li X, Han Y, Xi R* (2010). Polycomb group genes Psc and Su(z)2 restrict follicle stem 云顶集团(中国) self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling. Genes & Development 24(9):933-46.
27.Zhao R, Xi R* (2010). Stem 云顶集团(中国) Competition for Niche Occupancy: Emerging Themes and Mechanisms. Stem 云顶集团(中国) Rev. 6(3):345-50
28.Lin G, Xu N, Xi R* (2010). Paracrine unpaired signaling through the JAK/STAT pathway controls self-renewal and lineage differentiation of drosophila intestinal stem 云顶集团(中国)s. J Mol 云顶集团(中国) Biol 2(1): 37-49.
29.Xi, R* (2009). Anchoring stem 云顶集团(中国)s in the niche by 云顶集团(中国) adhesion molecules. 云顶集团(中国) Adh Migr 3(4): 396-401.
30.Lin G, Xi R* (2008) Intestinal stem 云顶集团(中国), muscular niche and wingless signaling. Fly (Austin). 2(6): 310-2.
31.Lin G, Xu N, Xi R* (2008). Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem 云顶集团(中国)s. Nature 455(7216):1119-23.
32.Zhao R, Xuan Y, Li X, Xi R* (2008). Age-related changes of germline stem 云顶集团(中国) activity, niche signaling activity and egg production in Drosophila. Aging 云顶集团(中国) 7(3):344-54.
33.Xi R, Xie T (2005). Stem 云顶集团(中国) self-renewal controlled by chromatin remodeling factors. Science310(5753):1487-9.
34.Xi R, Doan C, Liu D, Xie T (2005). Pelota controls self-renewal of germline stem 云顶集团(中国)s by repressing a bam-independent differentiation pathway. Development 132(24):5365-74.
35.Xi R, Kirrily D, Xie T (2005). Molecular mechanisms controlling germline and somatic stem 云顶集团(中国)s: similarities and differences (review). Curr Opin Genet Dev. 15(4):381-7.
36.Rawlings JS, Rennebeck G, Harrison SM, Xi R, Harrison DA (2004). Two Drosophila Suppressors of Cytokine Signaling (SOCS) differentially regulate JAK and EGFR pathway activities. BMC 云顶集团(中国) Biol. 15;5(1):38.
37.Song X, Wong, MD, Kawase E, Xi R, Ding BC, McCarthy J, Xie T (2004). BMP signaling from the niche directly represses the transcription of a differentiating gene, bag of marbles, in the germline stem 云顶集团(中国)s of Drosophila ovary. Development 131(6):1353-64.
38.Xi R, McGregor JR, Harrison DA (2003). A gradient of JAK pathway activity patterns the anterior-posterior axis of the follicular epithelium. Developmental 云顶集团(中国) 4(2):167-77.
39.McGregor JR, Xi R, Harrison DA (2002). JAK signaling is somatically required for follicle 云顶集团(中国) differentiation in Drosophila. Development 129(3):705-17.
